近期研究成果

Mar, 2016
En-Cheng Yang
Honey bees have the ability to detect the Earth’s magnetic field, and the suspected magnetoreceptors are the iron granules in the abdomens of the bees. To identify the sensing route of honey bee magnetoreception, we conducted a classical conditioning experiment in which the responses of the proboscis extension reflex (PER) were monitored. Honey bees were successfully trained to associate the...
Feb, 2016
Chen CY
Many causal mutations of intellectual disability have been found in genes involved in epigenetic regulations. Replication-independent deposition of the histone H3.3 variant by the HIRA complex is a prominent nucleosome replacement mechanism affecting gene transcription, especially in postmitotic neurons. However, how HIRA-mediated H3.3 deposition is regulated in these cells remains unclear. Here...
Feb, 2016
Lin SS
Bryophytes (liverworts, hornworts and mosses) comprise the three earliest diverging lineages of land plants (embryophytes). Marchantia polymorpha, a complex thalloid Marchantiopsida liverwort that has been developed into a model genetic system, occupies a key phylogenetic position. Therefore, M. polymorpha is useful in studies aiming to elucidate the evolution of gene regulation mechanisms in...
Nov, 2015
Chan SP
Primary microRNAs (pri-miRNAs) are cleaved by the nuclear RNase III Drosha to produce hairpin-shaped precursor miRNAs (pre-miRNAs). In humans, this process is known to be facilitated by the DEAD-box helicases p68 (DDX5) and p72 (DDX17). In this study, we performed a candidate-based RNAi screen in C. elegans to identify DEAD/H-box proteins involved in miRNA biogenesis. In a let-7(mg279) sensitized...
Sep, 2015
Tsai MH
Distinct microRNA (miRNA) and mRNA signatures were reported in nucleophosmin (NPM1)-mutated acute myeloid leukemia (AML). However, it remains unknown whether the mutation participates in the dynamic interaction between miRNA and mRNA. In this study, we aimed to investigate the role of NPM1 mutation in modulating miRNA-mRNA regulation (MMR). From the sample-paired miRNA/mRNA microarrays of 181 de...

研究成果亮點

[蜜蜂導航]計畫團隊是由生物與工程兩方面的研究人員所組成的跨領域研究群,進行「蜂群衰竭失調症(CCD)」探討,發現蜜蜂的消失是因為農藥不當使用所造成的後果。此研究成果不但廣受國際學術研究重視,並已備受歐盟採納。

相關研究更經由 Discovery 頻道拍攝為影片,於2013年12月全球首播,《台灣無比精彩:尖端農業》於12月30日首播,楊恩誠老師受邀於2014TEDxTaipei演說成果。